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AYURVEDIC HEALTH REMEDIES
AT ODDS WITH LOCAL COMMUNITYWHAT DOES IT MEAN? WHAT'S CAUSING IT? WHAT CAN YOU DO?
Are you prone to a problem with 'At odds with local community'?
Human nature is fundamentally flawed. Once the full significance of these flaws has been realized, it creates an opportunity to grieve. The grieving process brings us into loving acceptance of those around us and the reality of human suffering. When we can give ourselves completely to the healing of the human family, we will find new strength to engage the community from a place of compassion. When the liver is toxic, the body naturally wants to cleanse, including withdrawing from provocative relationships, creating bitterness towards others. The virtue of piety expresses gratitude to those who gave us life: God, family and country. While we may struggle with each of these things, it is also important to acknowledge that we derive our existence and identity from these as well. Try to remember this throughout your existential struggle with these factors in your life.
WHAT HAS ALREADY HELPED YOU HEAL AT ODDS WITH LOCAL COMMUNITY?Improve the accuracy of your recommendations by letting us know what is working.DIET REMEDIES FOR 'AT ODDS WITH LOCAL COMMUNITY'Neutral (Tridoshic)Cilantro  How does IT FEELS BETTER IT FEELS WORSE IT FEELS THE SAME We will use this information to better predict food that helps you. Reduces |
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SAVE IT
| BIOCHARACTERISTIC | DO YOU HAVE THIS IMBALANCE? |
|---|---|
| PITTA |  FIND OUTStatus UnknownTake these quizzes to find out if you have an imbalance of 'Pitta' dosha. |
HOT
Hot is identified by increased body temperature, metabolism, or inflammation.
|
FIND OUTStatus UnknownTake these quizzes to find out if you have an imbalance of 'Hot' guna. |
BITTER
Bitter is disagreeable and stimulating rejection, and a strong taste often associated with black coffee, dark chocolate, and most salad greens.
|
FIND OUTStatus UnknownTake these quizzes to find out if you have an imbalance of 'Bitter' taste. |
To learn more about the symbols above, click on them.
Are you prone to a problem with 'At odds with local community'?
Find your imbalances and create a diet for your Mind Stress Sleep by taking the
free mind stress sleep quiz.
DETOXICANT
An herb that decongests, dislodges or improves metabolization of toxins from the body, transforming or altering fluids to a more healthy state.ANXIOLYTIC
Herbs that help people suffering from anxiety or panic. They promote a state of calm and often improve sleep. Most anxiolytic herbs are also nervines.NERVINE
Herbs that specifically go to the nervous system and brain. They can help with stress, memory, early alzheimer's, even chronic pain.ALTERATIVE
Literally, an herb that restores the proper function of the body. In practice, alteratives are usually blood cleansers and blood chemistry balancers. They were traditionally used to revitalize and detoxify after a long winter.HEPATOPROTECTIVE
An herb that is capable of preventing liver damage.LIVOTONIC
An herb that strengthens the liver. It is helpful for people with a history of substance abuse, chronic liver issues from hepatitis and hemolytic anemias. Generally, liver tonics are oily, cool, sweet, mildly sour, or has beta-carotene.ADDRESS ISSUES IN STAGE OF DISEASE 2
AT ODDS WITH LOCAL COMMUNITY IS IN STAGE OF DISEASE 2 - AFFECTING BLOOD & EMOTIONSAffecting Blood: Initially, imbalances are localized, often in the digestive tract. As an imbalance grows, it starts to affect your body systemically, via the blood. If you have symptoms in this category it means that your imbalances are starting to spread, have entered the bloodstream, and are now systemic. Pay particular attention to the biocharacteristics, tastes, and doshas out of balance systemically, so you know how to strengthen your body as a whole, and reduce physical stress on your organs. At this stage of imbalance you will begin to experience generalized discomfort, imbalanced emotions, and may develop sensitivities to temperature. It may take several weeks of strict adherence to a specific remedial diet to clear blood level imbalances. Blood cleansing herbs may reduce symptoms. A several day cleanse may shorten the recovery time.
REDUCE THESE RELATED SYMPTOMS & HABITS
The following symptoms & habits may be related to 'At odds with local community'. See your quiz results for a computerized assessment of your body type. Please click on the symptoms below to learn more about them.Biocharacteristics of the 1,665 People Reporting At odds with local community
On average the biocharacteristics of people reporting At odds with local community were more aggravated than 87% of other symptoms. From the 1,665 people who reported At odds with local community in this research study of 74,671 individuals, average deviation in biocharacteristic levels were the following:BIOCHARACTERISTIC
AVG CLIENT LEVEL %
%CASES (#)
#IMBALANCE
Bitter Sign
Please login to see research statistics filtered on At odds with local community and Bitter.
100.0%
37.9% (631)
8,626 have Bitter constitution
Pitta Sign
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86.2%
34.8% (580)
10,540 have Pitta constitution
69.1%
26.6% (443)
7,528 have Sour constitution
68.8%
24.9% (414)
8,107 have Cold constitution
63.7%
32.1% (534)
11,554 have Vata constitution
60.3%
26.4% (440)
9,391 have Light constitution
45.2%
24.4% (407)
7,069 have Gooey constitution
43.6%
27.6% (460)
9,738 have Heavy constitution
35.2%
27.7% (462)
9,009 have Dry constitution
Hot Aggravates
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32.3%
21.2% (353)
7,949 have Hot constitution
29.8%
36.0% (599)
7,099 have Toxic constitution
28.1%
28.1% (468)
12,745 have Kapha constitution
Astringent
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26.8%
18.2% (303)
8,068 have Astringent constitution
22.4%
14.4% (240)
9,650 have Sweet constitution
14.7%
25.3% (421)
9,587 have Oily constitution
Pungent
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14.7%
16.2% (269)
6,802 have Pungent constitution
11.9%
29.0% (483)
7,179 have Salty constitution
Risk Factors of At odds with local community
Below you will see general risk factors as well as the greatest risk factors, i.e. those who were also more likely to report At odds with local community.
Overall, 4.83% of people surveyed in this research study reported At odds with local community.
SYMPTOM (Cases)
Cases With Both
% Reporting This
Increase from 4.83%
Review These Common Risk Factors
Feel underweight (2358)
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185
7.8%
60% more often
Feel overweight (25362)
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1116
4.4%
10% less often
Hyperactive, quick (19615)
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641
3.3%
30% less often
Fatigue / tired (16721)
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1096
6.6%
40% more often
Male (1336)
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130
9.7%
100% more often
Female (26227)
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1179
4.5%
10% less often
At odds with nationality / culture (212)
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61
28.8%
500% more often
At odds with church / religion (3636)
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752
20.7%
330% more often
Convulsions (156)
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29
Small number of cases
18.6%
290% more often
Vengeful / spiteful (383)
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63
16.4%
240% more often
Semen discharge in urine (130)
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21
Small number of cases
16.2%
240% more often
Oppressed / disempowered (3669)
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567
15.5%
220% more often
Hopeless (730)
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113
15.5%
220% more often
Unsupported (1057)
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158
14.9%
210% more often
Pain in testicles (251)
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36
Small number of cases
14.3%
200% more often
Unsupportive environment (3565)
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496
13.9%
190% more often
At odds with family (7184)
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989
13.8%
190% more often
Disappointed by life (1418)
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194
13.7%
180% more often
Unheard / misunderstood (1519)
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207
13.6%
180% more often
Fever (current) (294)
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39
Small number of cases
13.3%
180% more often
Self Mutilation (1881)
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250
13.3%
180% more often
Burning sense of shame (3769)
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492
13.1%
170% more often
Stole food or money to buy food (1041)
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136
13.1%
170% more often
Pretend Eating / Playing with Food (461)
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60
13%
170% more often
Guilty (1123)
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145
12.9%
170% more often
Preoccupied with sex / lust (2530)
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327
12.9%
170% more often
Undervalued / unrespected (1456)
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188
12.9%
170% more often
Defensive (225)
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29
Small number of cases
12.9%
170% more often
Restricting Water Intake (650)
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83
12.8%
170% more often
Oozing Sores on Skin (292)
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37
Small number of cases
12.7%
160% more often
Feel judged / criticized (8498)
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1044
12.3%
150% more often
Not smart enough (1117)
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136
12.2%
150% more often
Homesick (2646)
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324
12.2%
150% more often
Can't afford to buy food (1909)
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229
12%
150% more often
Trauma-induced overeating (1603)
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193
12%
150% more often
Sad (1382)
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165
11.9%
150% more often
Manic / giddy (2385)
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279
11.7%
140% more often
Lacking good counsel / mentor (7418)
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871
11.7%
140% more often
Night-time Ejaculation (369)
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43
Small number of cases
11.7%
140% more often
Pelvc Congestion Syndrome (227)
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26
Small number of cases
11.5%
140% more often
Blisters (609)
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70
11.5%
140% more often
Chronic Peeling (1173)
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135
11.5%
140% more often
Bluish / Purple Tongue (472)
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54
11.4%
140% more often
Scabies (211)
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24
Small number of cases
11.4%
140% more often
Weakness / Debility (3964)
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452
11.4%
140% more often
Whooping Cough (232)
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26
Small number of cases
11.2%
130% more often
Underconfident socially (1826)
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204
11.2%
130% more often
Moths in house (1228)
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137
11.2%
130% more often
Skin problems on nipples (827)
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92
11.1%
130% more often
Difficulty trusting others (1972)
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219
11.1%
130% more often
Dilated Pupil (518)
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57
11%
130% more often
Palpable Mass in Abdomen (267)
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29
Small number of cases
10.9%
130% more often
Jealous / envious (1049)
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114
10.9%
130% more often
Fear of getting sick (1065)
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116
10.9%
130% more often
Famine / Underfed in Childhood (1923)
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209
10.9%
130% more often
Blood or pus in mucus (462)
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50
10.8%
120% more often
Gray skin/lacking lustre (1056)
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114
10.8%
120% more often
Regret / remorse (1237)
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133
10.8%
120% more often
Burning/painful urination (1010)
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108
10.7%
120% more often
Poor discernment of temperature (1393)
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149
10.7%
120% more often
Grief (4696)
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501
10.7%
120% more often
Lungs Irritated / Inflamed (1038)
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111
10.7%
120% more often
Not attractive enough (1759)
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187
10.6%
120% more often
Mold in house (2546)
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269
10.6%
120% more often
Skin infections other (608)
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64
10.5%
120% more often
Withdrawn Emotionally (7826)
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819
10.5%
120% more often
Lonely / isolated (10442)
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1088
10.4%
120% more often
Feel rejected / unliked / unappreciated (11813)
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1231
10.4%
120% more often
Recent broken bone (182)
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19
Small number of cases
10.4%
120% more often
Painful rash (516)
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53
10.3%
110% more often
Premature Ejaculation (591)
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61
10.3%
110% more often
House dark (3837)
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395
10.3%
110% more often
Need constant social activity (1756)
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179
10.2%
110% more often
Non-healing sore / ulcer (816)
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82
10%
110% more often
Epilepsy (190)
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19
Small number of cases
10%
110% more often
Tongue frothy on edges (739)
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73
9.9%
110% more often
Acne - painful (1966)
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195
9.9%
110% more often
Lack of friendships (10390)
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1025
9.9%
110% more often
Easily hurt (1849)
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183
9.9%
110% more often
Blood thick / Congested lymph (1069)
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106
9.9%
110% more often
Illegal Drugs (marijuana, cocaine, etc) (3536)
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346
9.8%
100% more often
Past physical trauma (5997)
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585
9.8%
100% more often
Seizures (452)
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44
Small number of cases
9.7%
100% more often
Multiple chemical sensitivity (MCS) (2279)
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220
9.7%
100% more often
Heaviness in heart area (2680)
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259
9.7%
100% more often
Chronic Infection (1413)
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136
9.6%
100% more often
Tuberculosis/TB (135)
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13
Small number of cases
9.6%
100% more often
I'm different from others / unique (12424)
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1192
9.6%
100% more often
PTSD (Post traumatic stress disorder) (5247)
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502
9.6%
100% more often
Cockroaches in house (1453)
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140
9.6%
100% more often
Orangish skin (495)
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47
Small number of cases
9.5%
100% more often
Lacking love/affection (8438)
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804
9.5%
100% more often
Shaky / Jitters (4508)
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428
9.5%
100% more often
Doubt (2089)
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199
9.5%
100% more often
Sore eye muscles (2328)
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222
9.5%
100% more often
Change Difficult (5579)
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527
9.4%
90% more often
Fainting (2169)
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203
9.4%
90% more often
Chest Pain (2589)
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243
9.4%
90% more often
Skin problems on genitals (2395)
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224
9.4%
90% more often
Bleed less than other people (637)
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60
9.4%
90% more often
Pain on left side above heart (1752)
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165
9.4%
90% more often
Complications of Those Reporting At odds with local community
In this research study, people who report At odds with local community were likely to report the following:
REPORTS
CASES WITH BOTH
INCREASE
%
NORMALLY
At odds with church / religion
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752
+4.3 times
45%
10.56% (3,636 cases)
Prolonged bleeding when cut (Poor clotting)
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106
+3.4 times
6%
1.74% (1,259 cases)
Oppressed / disempowered
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567
+3.0 times
34%
11.3% (3,669 cases)
Self Mutilation
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250
+2.9 times
15%
5.17% (1,881 cases)
Bluish / Purple Tongue
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54
+2.9 times
3%
1.04% (472 cases)
Unsupportive environment
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496
+2.9 times
30%
10.49% (3,565 cases)
At odds with family
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989
+2.8 times
59%
21.02% (7,184 cases)
Burning sense of shame
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492
+2.8 times
30%
10.82% (3,769 cases)
Night-time Ejaculation
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43
+2.7 times
3%
1.1% (369 cases)
Exercising as punishment
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192
+2.7 times
12%
4.43% (2,175 cases)
Stole food or money to buy food
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136
+2.7 times
8%
2.96% (1,041 cases)
Pretend Eating / Playing with Food
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60
+2.7 times
4%
1.48% (461 cases)
Skin problems on nipples
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92
+2.6 times
6%
2.28% (827 cases)
Trauma-induced overeating
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193
+2.6 times
12%
4.62% (1,603 cases)
Preoccupied with sex / lust
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327
+2.6 times
20%
7.8% (2,530 cases)
Feel judged / criticized
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1044
+2.5 times
63%
24.97% (8,498 cases)
Manic / giddy
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279
+2.5 times
17%
6.75% (2,385 cases)
Can't afford to buy food
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229
+2.5 times
14%
5.63% (1,909 cases)
Famine / Underfed in Childhood
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209
+2.5 times
13%
5.25% (1,923 cases)
Restricting Water Intake
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83
+2.5 times
5%
2.02% (650 cases)
Homesick
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324
+2.5 times
19%
7.73% (2,646 cases)
Lungs Irritated / Inflamed
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111
+2.4 times
7%
2.86% (1,038 cases)
Seizures
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44
+2.4 times
3%
1.25% (452 cases)
Lacking good counsel / mentor
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871
+2.4 times
52%
21.79% (7,418 cases)
Blisters
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70
+2.4 times
4%
1.68% (609 cases)
Feel rejected / unliked / unappreciated
Please login to see research statistics filtered on At odds with local community and Feel rejected / unliked / unappreciated.
1231
+2.4 times
74%
31.22% (11,813 cases)
Poor discernment of temperature
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149
+2.4 times
9%
3.82% (1,393 cases)
Skin infections other
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64
+2.4 times
4%
1.7% (608 cases)
Weakness / Debility
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452
+2.3 times
27%
11.64% (3,964 cases)
Painful menstruation & menstrual cramps
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825
+2.3 times
50%
21.59% (13,471 cases)
Premature Ejaculation
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61
+2.3 times
4%
1.77% (591 cases)
Gray skin/lacking lustre
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114
+2.2 times
7%
3.14% (1,056 cases)
Moths in house
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137
+2.2 times
8%
3.59% (1,228 cases)
Non-healing sore / ulcer
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82
+2.2 times
5%
2.25% (816 cases)
Difficulty expectorating
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126
+2.2 times
8%
3.62% (1,399 cases)
Bleed less than other people
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60
+2.2 times
4%
1.81% (637 cases)
Sore eye muscles
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222
+2.2 times
13%
5.97% (2,328 cases)
Dilated Pupil
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57
+2.2 times
3%
1.38% (518 cases)
Chronic Peeling
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135
+2.2 times
8%
3.68% (1,173 cases)
Withdrawn Emotionally
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819
+2.2 times
49%
22.63% (7,826 cases)
Acne - painful
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195
+2.2 times
12%
5.56% (1,966 cases)
Chest Pain
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243
+2.2 times
15%
6.96% (2,589 cases)
Compulsive exercising
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153
+2.2 times
9%
4.18% (1,909 cases)
Lonely / isolated
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1088
+2.2 times
65%
30.19% (10,442 cases)
Family prevents career development
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345
+2.1 times
21%
9.83% (3,992 cases)
Solid foods aggravate abdominal pain
Please login to see research statistics filtered on At odds with local community and Solid foods aggravate abdominal pain.
130
+2.1 times
8%
3.75% (1,417 cases)
Pain on left side above heart
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165
+2.1 times
10%
4.69% (1,752 cases)
Vomiting
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95
+2.1 times
6%
2.82% (1,149 cases)
Liver Sore
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82
+2.1 times
5%
2.35% (883 cases)
501
+2.1 times
30%
14.11% (4,696 cases)
Heaviness in heart area
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259
+2.1 times
16%
7.6% (2,680 cases)
Mold in house
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269
+2.1 times
16%
7.61% (2,546 cases)
Guarding area of pain
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78
+2.1 times
5%
2.38% (886 cases)
No job security
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476
+2.1 times
29%
13.84% (5,754 cases)
Multiple chemical sensitivity (MCS)
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220
+2.1 times
13%
6.22% (2,279 cases)
House dark
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395
+2.1 times
24%
11.56% (3,837 cases)
Lack of friendships
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1025
+2.1 times
62%
29.87% (10,390 cases)
Past physical trauma
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585
+2.1 times
35%
16.93% (5,997 cases)
Eating after midnight
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319
+2.1 times
19%
9.2% (3,846 cases)
Need constant social activity
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179
+2.1 times
11%
5.33% (1,756 cases)
Illegal Drugs (marijuana, cocaine, etc)
Please login to see research statistics filtered on At odds with local community and Illegal Drugs (marijuana, cocaine, etc).
346
+2.1 times
21%
10.18% (3,536 cases)
Anal Spasm
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92
+2.1 times
6%
2.91% (1,145 cases)
Change Difficult
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527
+2.1 times
32%
15.58% (5,579 cases)
PTSD (Post traumatic stress disorder)
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502
+2.0 times
30%
14.64% (5,247 cases)
Tongue frothy on edges
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73
+2.0 times
4%
1.96% (739 cases)
Sticky saliva
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212
+2.0 times
13%
6.38% (2,391 cases)
Chronic Infection
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136
+2.0 times
8%
3.94% (1,413 cases)
Chronic Fatigue Syndrome (CFS)
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359
+2.0 times
22%
10.87% (4,107 cases)
Chewing and spitting food
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113
+2.0 times
7%
3.47% (1,294 cases)
Unemployed / underemployed
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558
+2.0 times
34%
16.88% (7,576 cases)
Blood or pus in mucus
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50
+2.0 times
3%
1.49% (462 cases)
Feel underweight
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185
+2.0 times
11%
5.47% (2,358 cases)
Slow, heavy digestion
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770
+2.0 times
46%
22.89% (21,898 cases)
Lack of Freedom / Independence
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617
+2.0 times
37%
18.42% (7,548 cases)
Skin problems on genitals
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224
+2.0 times
13%
6.49% (2,395 cases)
House hot
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267
+2.0 times
16%
7.99% (2,856 cases)
Smoking to suppress appetite
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333
+2.0 times
20%
9.99% (3,891 cases)
Blood thick / Congested lymph
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106
+2.0 times
6%
3% (1,069 cases)
I'm different from others / unique
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1192
+2.0 times
72%
36.15% (12,424 cases)
Gastrointestinal Bleeding
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46
+2.0 times
3%
1.51% (555 cases)
Painful rash
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53
+2.0 times
3%
1.51% (516 cases)
Tooth ache
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257
+2.0 times
15%
7.57% (2,997 cases)
Parasite passed in stool
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26
+2.0 times
2%
1.01% (353 cases)
Feel pain more than other people
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408
+2.0 times
25%
12.65% (4,736 cases)
Recurrent Vomiting
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62
+2.0 times
4%
2.03% (817 cases)
Pressure in eye
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207
+2.0 times
12%
6.09% (2,299 cases)
Even liquid foods aggravate abdominal pain
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93
+2.0 times
6%
3.06% (1,126 cases)
Sour sweat
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205
+2.0 times
12%
6.13% (2,316 cases)
Shaky / Jitters
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428
+2.0 times
26%
13.29% (4,508 cases)
Cockroaches in house
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140
+2.0 times
8%
4.09% (1,453 cases)
Fainting
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203
+2.0 times
12%
6.15% (2,169 cases)
Financially unstable
Please login to see research statistics filtered on At odds with local community and Financially unstable.
1005
+1.9 times
60%
30.79% (13,604 cases)
102
+1.9 times
6%
3.08% (1,160 cases)
Abdominal pain continuous
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104
+1.9 times
6%
3.09% (1,145 cases)
Burning/painful urination
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108
+1.9 times
6%
3.1% (1,010 cases)
Clammy Skin
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233
+1.9 times
14%
7.24% (2,812 cases)
Ringworm
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65
+1.9 times
4%
2.07% (712 cases)
Tooth Infection
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140
+1.9 times
8%
4.17% (1,644 cases)
Abdominal pain relieved by eating
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127
+1.9 times
8%
4.17% (1,562 cases)
Pain wakes you up at night
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140
+1.9 times
8%
4.18% (1,604 cases)
Lacking love/affection
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804
+1.9 times
48%
25.14% (8,438 cases)
WHAT'S NEXT?
DO YOU WANT TO LEARN MORE ABOUT YOUR UNIQUE BODY?
Then get your free body map!
Your body map contains a complete analysis of your Ayurvedic imbalances, organ by organ.
HOW AYURVEDA WORKS
ARE YOU WONDERING HOW AYURVEDA CAN HELP YOU?WHY IS AYURVEDA THE RIGHT SOLUTION?
Ayurveda strengthens the body, in addition to addressing the disorder. It take a holistic, systemic approach, instead of focusing only on the disorder in question. Ayurveda shows a person how to interpret signs and symptoms of imbalance, and how to address them using materials from home, so they can optimize their health on a continual basis. You can't take the doctor home with you, but you can take Ayurveda home with you. Ayurveda is the most advanced and easy to use home system for self healing with an exceptional focus on digestion.HOW DOES AYURVEDA WORK?
Ayurveda starts by identifying your body type, which identifies certain tendencies in your body to get sick (as well as identifying your strengths). It uses body type to determine the likely root causes of your disorders. Next, Ayurveda analyzes the nature of your disorder. It fits all your signs and symptoms into a pattern, expressed as a combination of biocharaceristics (gunas). For example, you may have a heat disorder, a cold disorder, or an oily disorder, etc. This simple categorical approach shows you how to correct systemic imbalances and strengthen your body as a whole.On Joyful Belly, we've created an extensive categorization of food so you can easily match food to your imbalanced biocharacteristics. By eating an optimal diet that balances your biocharacteristics, your whole body is strengthened and the conditions that created the disorder are removed. Once the root causes of the disease are removed, the disease lessens in strength or disappears altogether. Additional remedies - such as herbs and lifestyle practices - focused on the specific disorder, can greatly enhance your healing.
GET STARTED
To get started on your Ayurvedic journey, we first recommend that your find your body type by taking our free quiz. In Ayurveda, every solution is based on your unique body type, so by taking this quiz, you’ll get the best results.5 WAYS TO HEAL YOUR BODY
WITH AYURVEDA - FREE REPORT!
New to Ayurveda? Not sure how Ayurveda can help you?
This free report shows you 5 simple ways you can heal your body with Ayurveda.
It shows you simple, practical ways manage your health.
About the Author
John Immel, the founder of Joyful Belly, teaches people how to have a healthy diet and lifestyle with Ayurveda. His approach to Ayurveda exudes a certain ease, which many find enjoyable and insightful. John also directs Joyful Belly's School of Ayurveda , which specializes in digestive tract pathology & Ayurvedic nutrition. John and his wife Natalie recently published Explore Your Hunger: A Guide to Hunger, Appetite & Food.John's interest in Ayurveda and digestive tract pathology was inspired by a complex digestive disorder acquired from years of international travel, including his public service work in South Asia. John's commitment to the detailed study of digestive disorders reflects his zeal to get down to the roots of the problem. His hope and belief in the capacity of each & every client to improve their quality of life is nothing short of a personal passion. John's creativity in the kitchen and delight in cooking for others comes from his family oriented upbringing. In addition to his certification in Ayurveda, John holds a bachelor's degree in mathematics from Harvard University.
John enjoys sharing Ayurveda within the context of his Catholic roots, and finds Ayurveda gives him an opportunity to participate in the healing mission of the Church. Jesus expressed God's love by feeding and healing the sick. That kindness is the fundamental ministry of Ayurveda as well.
BOOKS BY JOYFUL BELLY
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* These statements have not been evaluated by the Food and Drug Administration.
The information and products on this website are not intended to diagnose, treat, cure or prevent any
disease.